Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication

Abstract The induction of antiviral innate immunity by systemic immunization with live virus promace injectable can be employed to positively impact the response to therapeutic vaccination.We previously demonstrated that systemic immunization with a non-replicating MVA encoding CD40 ligand (CD40L) enhances innate immune cell activation and function

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Change in household income and risk for attention deficit hyperactivity disorder during childhood: A nationwide population-based cohort study

Background: Childhood attention deficit hyperactivity disorder (ADHD) is reported to be more prevalent among socioeconomically disadvantaged groups in various countries.The effect of poverty on child development appears to depend on how long poverty lasts.The timing of poverty also seems to be important for childhood outcomes.Lifetime socioeconomic

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Heat Transfer in a Drilling Fluid with Geothermal Applications

The effects of various conditions on the fluid flow, particle migration and heat transfer in non-linear fluids encountered in drilling and geothermal applications are studied.We assume that the drilling fluid is a suspension composed of 2334-080 various substances, behaving as a non-linear complex fluid, where the effects of particle volume fractio

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Contribution of the Science, the Technology and the Innovation of the Universidad de Oriente to the Local Economic Revitalizing

The main objective of the research is to design a methodology to evaluate the contribution of the science, the technology and the innovation of universities to the local economic revitalizing.The scientific novelty resides in a sequence of procedures, based on administration, statistical and lexus rc4 mathematical modeling methods that constitutes

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